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Brain ischemia or stroke are the best examples of these disorders, as they are associated with intracellular ATP depletion [220,241,242], as well as hepatic encephalopathy, in which intracellular Na + concentration in astrocytes is markedly raised as a result of NH 3 /NH 4 + toxicity [243]

BhattaraiYWilliamsBBBattaglioliEJWhitakerWRTillLGroverMet alGut microbiota-produced tryptamine activates an epithelial G-protein-coupled receptor to increase colonic secretion