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Molecular analyses showed that CO23RFLC had acquired a marked increased expression of the MDR1 gene encoding for an efflux pump protein mainly responsible for the drug-resistance, due to a mutation in the transcription factor gene MRR1 [16] whereas CO23RFK had a homozygous mutation (S645Y substitution) in the FSK1 gene, responsible for the synthesis of glucan [17]

If the cellular mechanisms to scavenge ROS are inadequate, they can trigger free radical chain reactions that further damage proteins, lipids, and nucleic acids, potentially leading to various disease conditions (Craft et al

Cognitive and neurological Semax A neuropeptide originally developed in Russia, studied for cognitive performance, focus, and neuroprotection

doi: 10.1023/a:1023259102279