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Description
Here we defined a signature of 59 genes and two metabolites (GSH and NADP) that is robustly associated with NRF2 dependency across an extensive panel of cancer cell lines

10.1016/j.mce.2014.08.012 117 TakemuraY.OsugaY.YoshinoO.HasegawaA.HirataT.HirotaY.et al (2007)

PHGDH is key to a prognostic multigene signature and a potential therapeutic target in acute myeloid leukemia

Support for a healthy liver*
