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10.1530/endoabs.109.EP40 52 MiyamotoT.HiramotoS.KantoA.TsubotaM.FujitaniM.FukuyamaH.et al (2021)

This molecule, known as divertin, blocks MLCK1-mediated phosphorylation of perijunctional MLC, thereby preventing subsequent occludin endocytosis and increases in leak pathway permeability 141

Ann Pharmcother

Conclusion The future of brain energy metabolism research lies in addressing these unsolved questions through a multidisciplinary approach that combines advanced technologies with a deep understanding of cellular and systemic metabolism