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When tesamorelin binds to GHRH receptors on pituitary somatotroph cells, it triggers the adenylate cyclase-cAMP signaling cascade, which stimulates the synthesis and secretion of endogenous growth hormone in pulsatile bursts that mirror the body natural rhythm

Physiology, cellular receptor StatPearls StatPearls Publishing 2023 Accessed 22 Jun 2023 Moraga-Cid G, San Martn VP, Lara CO, et al

Pharmacogn J 6:6 Vaibhav S, Subodh D, Vigyan S (2019) Hypolipidemic activity of stem bark of Ailanthus excelsa Roxb in Triton WR 1339 induced hyperlipidemic rats

Unless otherwise explicitly defined, a substituent group, as used herein, includes a functional group selected from one or more of the following moieties, which are defined herein: The term hydrocarbon, as used herein, refers to any chemical group comprising hydrogen and carbon