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Meanwhile, the release of CXCL10-bearing EVs from hepatocytes was induced by mixed-lineage protein kinase 3 (MLK3) activation [107]
Furthermore, glucose metabolism and targeting glycolytic enzymes can influence the activity of transcription factors such as NF-B, HIF-, and TGF- , which can influence the expression of genes involved in inflammation and cartilage breakdown
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Kidane D, Chae WJ, Czochor J, Eckert KA, Glazer PM, Bothwell AL, Sweasy JB
