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Ask your doctor for a total B12 test, as well as a screening for one or two of these compounds: holotranscobalamin, methylmalonic acid (MMA), and homocysteine

The strongest evidence is in animal research

Alcoholism: Clinical and Experimental Research, 33 (9), 1489- 1507.

Exercise, which is known to improve menopausal metabolic health, increases MOTS-C levels by 11.9 times in muscle tissue, suggesting that some of the metabolic benefits of exercise during menopause may be mediated through MOTS-C pathways
