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The mechanisms remain unclear, potentially involving rapid weight loss affecting hormones or direct effects, but further research is needed

Side effects and safety considerations Pyridoxine is generally safe when dosed appropriately, but it is not without risks

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Who May Be at Greater Risk of Adverse Effects Over Time Older adults, people with prior pancreatitis or gallbladder disease, those with cardiovascular conditions or diabetic retinopathy, and individuals with renal impairment face heightened risk and require closer monitoring