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Acknowledgements This work was supported by the Intramural Research Program of the NIH/National Institute of Environmental Health Sciences 1Z01ES090079

However, do not apply heat directly to the elbow joint if there is a sensation of burning pain, as this typically indicates tendon inflammation that could worsen with heat

KPV (Lysine-Proline-Valine) is a naturally occurring tripeptide derived from alpha-melanocyte-stimulating hormone (-MSH), a hormone known for its potent anti-inflammatory and immune-regulating properties

Given that mature spines are thought to be associated with increased long-term potentiation (LTP) and memory [284], the loss of these mature spines may be the mechanism by which AMPH sensitization impairs hippocampal-based memory