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Bactericidal and cytotoxic properties of silver nanoparticles

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The oxidative branch produces both ribose-5-phosphate (R5P), which is precursor for nucleotide synthesis, and NADPH, which is not only required for biosynthesis reactions but also for antioxidant response function
RNR subunit expression is controlled by the cell cycle machinery to match the need for nucleotide synthesis to cell proliferation (Eriksson et al, 1984
