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A ketogenic drink improves cognition in mild cognitive impairment: results of a 6-month RCT

[DOI] [PMC free article] [PubMed] [Google Scholar] Cave M.C., Hurt R.T., Frazier T.H., Matheson P.J., Garrison R.N., McClain C.J., McClave S.A

Mitochondria also harbor glucocorticoid receptors (GRs)that, upon activation, bind to the mitochondrial DNA glucocorticoid response element (GRE) sequence motif to regulate mitochondrial rRNA synthesis and gene expression [87, 88]

Whilst some research suggests modest benefits, especially in mild to moderate ED, the evidence remains mixed and amino acids are not recommended as first-line treatment in UK clinical guidance