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Description
By inhibiting NNMT, 5-Amino-1MQ has been shown to increase intracellular NAD+ and SAM availability, upregulate polyamine flux enzymes, and alter histone methylation patterns in preclinical adipocyte models
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NNMT plays a crucial role in the methylation of nicotinamide, affecting intracellular nicotinamide adenine dinucleotide (NAD+) metabolisma key cellular cofactor for redox reactions, DNA repair, and transcriptional regulation
Shin, N
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