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Notably, IGFBP-2, IGFBP-3, and IGFBP-5 participate in a wide variety of ncRNA-regulated pathways, with both stimulatory and inhibitory effects on cancer cell functions
10.1007/s10787-021-00843-6 59 PengS.GaoJ.LiuW.JiangC.YangX.SunY.et al (2016)
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However, carrying excess body fat, especially visceral fat that accumulates around internal organs, can significantly increase the risk of heart disease, diabetes, and other chronic conditions
