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There were significant results at 1-year follow-up: a mean improvement of 17 in penile curvature at 36 weeks and an improvement in erectile function

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L-2-HGA-associated genetic variants inhibit the activity of L-2hydroxyglutaric acid dehydrogenase (L2HGDH), an important mitochondrial enzyme involved in the metabolic processes of glutamate and glutamine, which oxidizes the L-2-hydroxyglutarate into -ketoglutarate [46] (Fig
