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Nevertheless, it has also been demonstrated that glucose deficiency, activation of the system Xc system, high expression of SLC7A11, elevated NADP+/NADPH ratio, extensive NADPH consumption, cystine accumulation, and decreased GSH levels collectively drive ferroptosis [97]

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Meta-analysis: glutathione-S-transferase allelic variants are associated with alcoholic liver disease

References: He L, Feng D, Guo H, Zhou Y, Li Z, Zhang K, Zhang W, Wang S, Wang Z, Hao Q, Zhang C, Gao Y, Gu J, Zhang Y, Li W, Li M
