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While the molecular basis for these interactions remains largely unexplored, there is circumstantial evidence that IGF-1 signaling is involved in the hair growth cycle and the differentiation of hair shafts [11]
10.1210/jc.2017-02457 J
That makes it necessary for strong bones
Since DNA damage in the gametes could have serious consequences in reproduction [30], the sperm may also play a role in complicated pregnancies
