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In chronic hepatitis B and C were also demonstrated elevated levels of IGF-1 and lowered levels of IGF BP-3 (97)

doi: 10.3389/fimmu.2021.695674

This is different from the oral administration route, which has a low bioavailability due to a first-pass metabolism of the drug [25]
Ritter JK, Yeatman MT, Ferreira P, Owens IS
