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Therefore, endogenous GIP seems to retain a role in postprandial glucose regulation following gastric sleeve but when the first part of the small intestine is bypassed (Roux-en-Y gastric bypass) endogenous GIP does not contribute to the postprandial glucose regulation (79)

The average decline in HbA1c among treatment groups was 1.7 to 1.9 percentage points, more than double the placebo groups 0.8 percentage-point decrease
Third, the IRAs small molecule vs