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Description
GLP1 therapies may exert antiinflammatory effects by reducing proinflammatory cytokines, which could theoretically lessen inflammatory stress on neural circuits involved in mood

New research reveals how GLP-1 medications are reshaping the treatment landscape for conditions affecting the heart, kidney, liver, and more, hinting at a new era in chronic disease management

Hospitalisation for heart failure, reported in 5 of the 11 studies, showed a smaller but statistically significant reduction (HR (95% CI): 0.88(0.770.99)

Additional well-designed, prospective studies are needed to confirm the potential benefit of GLP-1 receptor agonist treatment for patients with advanced CKD or ESKD." For further information: DOI: 10.1001/jamanetworkopen.2022.1169 Keywords: CKD, ESKD, GLP-1 receptor agonist, DPP-4 inhibitors, type 2 diabetes, JAMA Network Open, chronic kidney disease, end-stage kidney disease, National Health Insurance Research Database of Taiwan, MACCE, Mortality rate