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However, the majority of women suffering from PCOS and obesity fail to significantly reduce their body weight with lifestyle intervention
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Kalra et al., Fixed-dose combination in management of type 2 diabetes mellitus: Expert opinion from an international panel, J
In addition, the application of exendin-4, a GLP-1RA in obese mice triggered by diet restores C1q/TNF-related protein 3 (CTRP3) expression in keratinocytes, thereby inhibiting STAT3 phosphorylation via lysosomal-associated membrane protein 1 (LAMP1) and alleviating the psoriatic symptoms induced by imiquimod treatment [204]
