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By combining free iron in a complex, DFO protects Fe 3+ from reduction and avoids the formation of ROS through Fenton reaction ( in ex vivo perfused hearts (Kobayashi et al., 2018)

The Phase II Detoxification Pathway Phase II is all about removing the freed-up toxic waste created in Phase I

In agreement, it was shown that increased HO-1 activity markedly reduces the chemotactic recruitment of monocytes after exposure to oxidized LDL

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