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Velarde MC, Aghajanova L, Nezhat CR, Giudice LC
It is of concern that the efficacy of MSCs is greatly limited by the local inflammatory microenvironment following SCI

In RNAi transgenics, this effect is expected to have a detrimental impact

Additionally, potential signaling pathways such as SIRT1, PI3K/Akt, and gene expression changes warrant deeper investigation
