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Description
Lysosomal hydrolases, such as cathepsin B, D, and L, are involved in the cleavage of autophagic substrates, whereas the resulting molecules are transported back to the cytosol for nutrient recycling (363)
Glutathione for detox then steps in during Phase II, where it conjugates with these modified toxins, attaching itself to them and transforming them into water-soluble compounds [5]
Circulating cytokines like IL-1, IL-6, and TNF- cross or breach the BBB, augmenting neuroinflammatory cascades
These mammalian-based systems express soluble, functional proteins that are post-translationally modified, unlike E
