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However, this is preliminary

5.2.1 The regulatory role of exercise on oxidative stress Aerobic exercise (such as running, swimming, etc.) improve cardiorespiratory function and enhances blood circulation, strengthening the efficacious delivery of oxygen and nutrients, thus strengthening the brain and other tissues ability to combat oxidative stress (You et al., 2022)

Spermine was shown to drive PD-L1 expression through -catenin phosphorylation mediated by p-Akt

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