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Brain metabolites are secreted and infiltrated into CSF to regulate the entire central nervous system and even organs throughout the entire body ( Recent research suggests that there is a class of neurons in contact with CSF on the ependyma called CSF-contacting neurons (CSF-cNs), and the location of CSF-cNs and ciliary morphology suggests that they sense physical and chemical signals in the CSF (Orts-DelImmagine and Wyart, 2017)

[DOI] [PubMed] [Google Scholar] 5.Chaudhari K.S., Tiwari N.R., Tiwari R.R., Sharma R.S

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