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N-Acetylcysteine: a safe antidote for cysteine/glutathione deficiency
Decreased expression of GPx1 by iberin results in an accumulation of detrimental concentrations of ROS (measured by DCF fluorescence) that inhibits cell proliferation, induces cell cycle arrest, and promotes apoptosis, whereas the forced upregulation of GPx1 or antioxidant treatment attenuates these therapeutic actions [143]
& Prohaska, J
Iron uptake in tumor cells primarily relies on TFR1 and DMT1 ( 3+
