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Taken together, C57BL/6J mice are more susceptible to oxidative hepatic injury compared with 129X1/SvJ mice after acute arsenic exposure, which is closely associated with arsenic methylation pattern of the two strains.

The cause of the disease is not clear, but genetic factors related to the polymorphism of the HLA-Cw6 gene are most often indicated

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Gently massage it into the affected areas until fully absorbed
