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Traditional Chinese medicine formulations, such as Simiao Pills, demonstrate multi-component synergy (phenolic acids, terpenoids, and alkaloids) in mitigating hyperuricemia and renal injury, mediated through anti-inflammatory effects and renal transporter modulation (Zeng et al., 2024)

Studies suggest that nasal bioavailability for peptides can range from 30% to 70%, with significant variation between individuals and even between administrations in the same person

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For example, the choroid plexus, a structure in the brain that produces cerebrospinal fluid, may serve as a gateway for monocyte infiltration into the CNS [170]