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Using a similar strategy, exocyclic enones displaying antitumor activity were produced by a GSH-dependent reaction catalyzed by GST (Hamilton et al., 2002, 2003)

[DOI] [PubMed] 206.Hartman AL, Gasior M, Vining EPG, Rogawski MA

doi: 10.1186/s10020-025-01208-3 133 WallenZDStoneWJFactorSAMolhoEZabetianCPStandaertDGet al

The uptake of Caco-2 cells was 0.349 mg/g, significantly higher than that of glabridin (0.039 mg/g)
