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Collagen is too large a molecule to penetrate the skin, which means topical collagen doesnt stimulate collagen production on a cellular level the way collagen supplementation will. 2

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Bibcode:1990FEBSL.267..189A

Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models
