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The effects of BPC-157 on HUVECs might be mediated by activation of ERK1/2 phosphorylation, leading to enhanced cell proliferation, migration, and tube formation

Since the valinomycin synthetase Vlm shows the same genetic architecture as Ces, it is tempting to speculate that the novel mechanism of non-ribosomal peptide assembly proposed in this study is not a specificity of the cereulide synthetase but a more common logic for biosynthesis of ester bond containing NRPS products, thereby contributing to biodiversity of natural depsipeptide products

PloS One (2015) 10:E0113192