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Following its nuclear entry, Nrf2 binds to antioxidant response elements, thereby inducing expressions of heme oxygenase-1 (HO-1), superoxide dismutase-1 (SOD1), NAD(P)H quinone oxidoreductase-1 (NQO1), among other oxidases

Thus, we used scopolamine (2 mg/kg of animal b.w) to induce AD-like cognitive impairment in mice, and we also used Tac (10 mg/kg of animal b.w), an approved AChE inhibitor, as positive control

However, it's essential to remember that natural remedies may take longer to show results compared to medicated creams, so patience and consistency are key

However, this expansion has resulted in an influx of counterfeit or inferior items, particularly in the internet market