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Description
doi: 10.1073/pnas.2205044120
To check whether the attenuation of hepatotoxicity was dependent on GSDME inhibition, we compared transaminase activities and inflammatory cytokines levels in WT and Gsdme / mice in the presence or absence of MeCbl
Cardiomyocyte apoptosis and cardiac fibrosis were increased in the mouse model of diabetic cardiomyopathy, the protein expression of Nrf2 and HO-1 was reduced in left ventricular cardiomyocytes
On the other hand, large animals such as nonhuman primates or pigs have gyrencephalic brains and abundant WM that make them closer to humans (369)
