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Additionally, many ME/CFS and Long COVID patients show an imbalance in gut bacteria, formerly known as dysbiosis, with fewer beneficial species like Faecalibacterium and Bifidobacterium, and more pro-inflammatory Gram-negative bacteria

Methodologies for modeling both acute and chronic muscle injury have been comprehensively summarized in previous reviews (Grounds et al., 2002

Systemic therapy was only recommended in cases of life-threatening progressive disease or in cases of compression of vital structures or organ dysfunction in the setting of progressive disease
