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Description
The potential metabolism-immune-neuro interaction framework of PEM is based on multi-level molecular crosstalk: mitochondrial dysfunction generates DAMPs that activate innate immune pathways (NLRP3, NF-B) to induce peripheral inflammation

It helps repair and manage symptoms, but outcomes depend on the severity of nerve damage

10.3390/IJMS23169034 26 LaiW

Reducing the availability of endogenous copper and glucose for cascade starvation therapy and chemodynamic therapy
