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every claim about the two compounds working better together is a mechanistic inference built on the individual data, not a head-to-head result

G protein-coupled receptor ghrelin growth hormone secretagogue receptor pharmacology receptor dimerization Significance Statement The growth hormone secretagogue receptor, a key component of the ghrelin system, is important in many processes, including feeding behavior, stress, and reward

Stephenson K, Kennedy L, Hargrove L, et al

Ionotropic and Metabotropic Mechanisms of Allosteric Modulation of 7 Nicotinic Receptor Intracellular Calcium
