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47 (9), 40834094 (2019) ( Epub 2019/08/23 )

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Unlike the other common amino acids, rotation about the C-N bond in proline is not possible due to the structural constraint of the five-membered ring

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Parts of the N-terminal alanine acceptor and the phenylalanine donor also fall within this helical turn, and careful analysis of the structure indicates there are 3.6 amino acid units per turn

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Hynes RO

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