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Description
This inhibitor also enhanced GLUT4 translocation, and phosphorylation of Ser473-Akt, p85-PI3K, Tyr1361-IR- and Tyr612-IRS-1 in the skeletal muscle of db/db mice, suggesting that 1-deoxynojirimycin enhances insulin sensitivity through the IRS-1/PI3K/Akt pathway and increases the translocation of GLUT4 to the membrane, leading to an increase in muscle glycogen content (62,63)

Dysfunctional High-Density Lipoprotein in Patients on Chronic Hemodialysis

[Crossref] [PubMed] Tsambarlis P, Levine LA

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