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No statistically significant mean differences in behavior tests or in glutathione status were identified between active and placebo groups. However, detailed data analysis suggests that methyl B12 may alleviate symptoms of autism in a subgroup of children

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Disorders of cobalamin (vitamin B12) metabolism: emerging concepts in pathophysiology, diagnosis and treatment

All mice received 2 days of 10 mL/kg body weight sterile saline subcutaneous injections before beginning the treatment phase to allow for acclimation to the handling and stress associated with injections