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(2016) 113:E21422151

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Curcumin may be neuroprotective after ischemia and reperfusion injury [96]

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In this integrated manner, CoQ 10 limits the production of lipid peroxyl radicals and protects the circulating lipoproteins, the cellular membrane proteins, the mitochondrial DNA, and the ETC membranes [26,34,35,36]

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On the one hand, high expression of EC-SOD inhibited the increase in methylase activity and downregulated the expression of recombinant DNA methyltransferase 1(DNMT1) and DNMT-3b, thereby inhibiting the increase in HIF1 and biological oxidants

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