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In addition, CoQ10 has been observed to significantly decrease the levels of oocyte apoptosis, double-strand breaks, and DNA damage ( In addition, research has found that high levels of CoQ10 in the follicular fluid were associated with improved embryo morphokinetic parameters and higher pregnancy rates ( in vitro maturation rate of immature oocytes in patients with endometriosis compared to those who do not receive the supplement (Romero et al., 2020)

J Biol Chem 2004;279:55008-16

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These studies suggest that ammonium accumulation may induce programmed cell death of immune cells within TME, such as NK cells, through oxidative imbalance and mitochondria-mediated autophagy, thereby promoting immune evasion by prostate cancer cells