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2 Pathogenesis of pulmonary fibrosis Tissue repair following injury is an inherent biological mechanism that restores tissue integrity through the organized replacement of damaged or deceased cells (Figure 1: the initial sustained injury phase, the inflammatory cell migration phase, the fibroblast migration/proliferation/activation phase and finally, the excessive deposition of ECM and fibrosis phase

Cell counting kit-8 (CCK-8) cell viability measurement HSCs were plated in 96-well plates at 3000 cells per well, treated with MSCs conditioned medium (MSCs-CM), Fer-1 (1 M), and Eras (10 M) for 48 h, then incubated with CCK-8 reagent for 1 h before measuring OD at 450 nm

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