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They can cause damage to cells if they arent properly controlled by our natural antioxidant systems

doi: 10.1007/s12192-020-01071-7

Well-absorbed orally

oxymetazoline topical (Rhofade) niacinamide topical The drug brimonidine topical (Mirvaso) can also be used but it is known for sometimes leading to rebound redness that can be worse than original symptoms
