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Pharmacological autophagy inhibition enhances HCC susceptibility to TrxR suppression, positioning TrxR as a promising chemotherapeutic target for HCC management (147)

EAAT1 is predominantly expressed in astrocytes, while EAAT2 (also known as glutamate transporter-1 (GLT-1)) is found in both astrocytes and neurons

N -acetylcysteine (NAC) is a synthetic derivative of the endogenous amino acid L-cysteine (Fig

For stomach lavage, stomach, small intestine, colon and small intestine lavage (calibration samples and QCs (of the respective matrix) or PK samples), 50 l of a sample was extracted with 50 l of a 50:50 mixture of acetonitrile and methanol containing 12.5 ng ml 1 of caffeine as internal standard for 15 min at 800 rpm on an Eppendorf MixMate vortex mixer