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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Pan M, Wang G, Zhou L, et al

Targeting tumors with IL-21 reshapes the tumor microenvironment by proliferating PD-1intTim-3-CD8+ T cells
These findings support the further investigation of glutamine-coupled organophilin (IV) compounds as potential chemotherapeutic agents for the treatment of colon cancer [186]

Oxidative stress due to infections is further aggravated by the malabsorption of dietary antioxidants in the intestine and the inability of cells with the CFTR mutation to efflux GSH [91]