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We will cover what we know from available data and clinical experience, what we do not know due to limitations in human trials, and what practical steps reduce risk the most

We also investigate their preclinical and clinical insights for primary liver cancer intervention, and explore the significance of using Wnt/-catenin mutations as a biomarker to predict resistance in immunotherapy

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[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Canto C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J
