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doi: 10.3389/fmicb.2022.956516 [DOI] [PMC free article] [PubMed] [Google Scholar] 100
10.3389/fmicb.2020.01865 Front
For example, Bifidobacterium animalis F1-7 can upregulate acetylcarnitine levels in the gut, thereby downregulating the TLR4/NF-B pathway and reducing lipid accumulation and inflammation in foam cells, leading to a reduction in atherosclerotic plaque accumulation [129]
L-Carnitine homeostasis reflects the balance among intestinal absorption, biosynthesis in several tissues, including the liver, kidney, and brain, renal reabsorption, and muscular storage (Evans and Fornasini, 2003), (Longo et al., 2016), and is maintained by the carnitine/organic cation transporter (OCTN) 2 expressed in these tissues (Tamai, 2013)
