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doi: 10.1016/j.vph.2017.05.005
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Additionally, Res alleviated PM2.5-induced lung inflammation and fibrosis by inhibiting autophagy and NLRP3 inflammasome activity, reducing IL-1 in BEAS-2B cells ( 3.2.4 Terpenoids Triptolide, a bioactive diterpene from Tripterygium wilfordii , was shown to downregulate mRNA and protein expression of -SMA, type I collagen, FN, and vimentin, inhibiting lung fibroblast migration and transformation
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