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Nrf2, a nuclear transcription factor, translocates to the cell nucleus to upregulate HO-1, converting heme to biliverdin, iron, and CO [108]

Yuan H, Li X, Zhang X, Kang R, Tang D

2.4.2 Citrus reticulata hesperidin Hesperidin (HSD) combats oxidative stress primarily by activating the Nrf2/ARE pathway and inhibiting NF-B signaling

In this post, well explore this treatment in detail to help you understand how it works and why it could be the right choice for you
