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Role of m6A modification in female infertility and reproductive system diseases

Oxidative stress occurs following an imbalance of the bodys antioxidant defence mechanisms and excessive generation of free radicals, and is involved in various pathologies such as diabetes, atherosclerosis, hypertension, neurodegenerative diseases, inflammation, and cancer (Oboh et al., 2016)

Glutathione can be found in different forms, including reduced glutathione (GSH), oxidized glutathione (GSSG), and glutathione precursors such as N-acetyl-cysteine (NAC) and alpha-lipoic acid (ALA)

This accumulation further poisons mitochondrial enzymes and exacerbates immune dysregulation